Parameters of perineural invasion in radical prostatectomy specimens lack prognostic significance
نویسندگان
چکیده
منابع مشابه
Prognostic significance of perineural invasion in patients who underwent radical prostatectomy for localized prostate cancer.
PURPOSE Perineural space invasion (PNI) is an important mechanism for progression of cancer through the prostatic capsule, the prognostic significance of PNI remains controversial. The purpose of the present study was to assess the prognostic significance of PNI between prostate biopsy and radical prostatectomy (RP) samples of patients affected by clinically localized prostate cancer (PCa). M...
متن کاملrelationship between perineural invasion in prostate needle biopsy specimens and pathologic staging after radical prostatectomy
conclusions although the presence of pni in prostate biopsy is accompanied by higher surgical stages, pni is not an appropriate independent factor in risk stratification. patients and methods this cross-sectional study was conducted using a sample of 109 patients who attended a tertiary health care center from 2008 to 2013. the selection criteria were pni in prostate biopsy with gleason scores ...
متن کاملRelationship Between Perineural Invasion in Prostate Needle Biopsy Specimens and Pathologic Staging After Radical Prostatectomy
BACKGROUND Prostate cancer is the second most common malignancy among men worldwide and the sixth cause of cancer-related death. Some authors have reported a relationship between perineural invasion (PNI), Gleason score, and the invasion of peripheral organs during prostatectomy. However, it is not yet clear whether pathological evidence of PNI is necessary for risk stratification in selecting ...
متن کاملDo margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens.
PURPOSE The prognostic significance of positive surgical margins (PSM) in radical prostatectomy (RP) specimens remains unclear. While most studies have concluded that a PSM is an independent adverse prognostic factor, others report that surgical margin status has no effect on prognosis. One reason for these discordant conclusions is the variable number of patients with a PSM who receive adjuvan...
متن کاملDo margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. - PubMed - NCBI
The prognostic significance of positive surgical margins (PSM) in radical prostatectomy (RP) specimens remains unclear. While most studies have concluded that a PSM is an independent adverse prognostic factor, others report that surgical margin status has no effect on prognosis. One reason for these discordant conclusions is the variable number of patients with a PSM who receive adjuvant therap...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2008
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2008.81